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Won stem cells with citric acid

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Won stem cells with citric acid

For the procurement of stem cells of human embryos have been required which is highly controversial. Now there is new research that could make this way unnecessary. Researchers are already talking about a new era of stem cell biology. With some researchers acid cells have returned to a cheap jordan 1 shoes kind of embryonic state, thus generating stem cells. The recovered cells could develop into almost any cell type further, scientists from Japan and the U.S. report in the British journal Nature. So far, specific genes or proteins for reprogramming were necessary. The process of the team to Haruko Obokata from Riken Center for Developmental Biology in Kobe, Japan is much simpler: the researchers treated skin cells of newborn mice with a solution of a weak citric acid. Here, some cells developed to an earlier, undifferentiated state of development. The researchers speak of STAP cells (stimulus-triggered acquisition of pluripotence / triggered by a stimulus formation of pluripotency). Using genetic markers, they have shown that these STAP cells have properties similar to embryonic stem cells. However, they can multiply itself much worse. Cells with far-reaching FähigkeitenIn a further experiment discovered Obokata and his staff, that the skills of STAP cells are still able to pass: In a culture solution, as used for the propagation of embryonic stem cells, the cells began to better reproduce and developed structural and genetic properties embryonic stem cells. Planting the researchers STAP cells into a mouse embryo, a so created animals, their different tissue types were composed of both descendants of the own cells, as well as from those of the STAP cells. The scientists also raise a special property before: STAP cells developed even in a kind of trophoblast an outer layer of cells of embryos, which is important for the implantation into the uterus. This indicates that this is a particularly broad differentiation capacity of the cells, the team writes. Transferable to humans? The reprogramming of somatic cells into a state where they can develop as embryonic stem cells to many different tissue types, was previously managed only by biochemical and genetic manipulations. The process of creating these young cells by simple acid stress, air jordan spizike for sale opens up new possibilities to produce one day the patient's own stem cells, Austin Smith of Cambridge University commented in Nature. However, one must bear in mind that attempts have been made only with immature mouse cells. It remains to be seen whether this also succeed in other organisms, especially humans. From A new era of stem cell biology, says the stem cell researcher Dusko Ilic from Kings College London. Whether human cells respond in a similar manner to such influences, however, must be shown he conceded also a. It (the process) does not bring closer the stem cell-based therapy, he said. One must just be careful on the way to clinical use, as with other methods of cell reprogramming. These include the induced pluripotent stem cells developed in 2006 (iPS cells), which have not yet led to an approved therapy. Unlike embryonic stem cells, however, no embryo must be destroyed for STAPoder iPS cells. So should not lead to major ethical concerns, the new cells. The approach of the research team calls Ilic revolutionary. It is a fundamental change in the give way, as scientists consider the interaction of environment and genes.

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